DO NOT use Acts if:
- are allergic to any ingredient in Actos
- have moderate to severe heart failure
- have type 1 diabetes
- have a history of liver problems, including jaundice (yellowing of the skin or eyes), during treatment with a similar medicine called troglitazone.
Contact your doctor or healthcare professional immediately if any of these apply to you.
Some diseases can interact with Actos. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breastfeeding
- if you are taking any prescription or non-prescription medicine, herbal preparation, or dietary supplement
- if you are allergic to medicines, foods or other substances
- if you have diabetic ketoacidosis (a serious problem associated with diabetes)
- if you have a history of liver problems, abnormal liver function tests, heart problems (for example, congestive heart failure [CHF]), or eye or vision problems
- if you have problems with swelling (edema).
Some medicines can interact with Actos. Tell your doctor if you are taking any other medicines, especially any of the following:
- Gemfibrozil, insulin or oral antidiabetic medicines (eg glipizide) because it may increase the risk of low blood sugar
- Rifampicin because it can decrease the effectiveness of Actos, causing an increase in blood sugar
- Anticoagulants (eg warfarin) because the risk of their side effects may be increased or their effectiveness may be decreased with Actos.
This may not be a complete list of all interactions that can occur. Ask your doctor if Actos can interact with other medicines you take. Consult your doctor before starting, stopping, or changing the dose of any medicine.