DOSAGE AND ADMINISTRATION
ADVAIR DISKUS should be administered as 1 inhalation twice daily orally only. After inhalation, the patient should rinse the mouth with water without swallowing to help reduce the risk of oropharyngeal candidiasis.
More frequent administration or a greater number of inhalations (more than 1 inhalation twice daily) of the prescribed strength of ADVAIR DISKUS is not recommended, as some patients are more likely to experience adverse effects with higher doses of salmeterol. Patients using ADVAIR DISKUS should not use additional LABAs for any reason.
Asthma
If asthma symptoms appear between doses, an inhaled short-acting beta2-agonist should be taken for immediate relief.
- Adult and adolescent patients 12 years of age and older
- For patients 12 years of age and older, the dose is 1 inhalation twice daily, approximately 12 hours apart.
- The recommended starting doses of ADVAIR DISKUS for patients 12 years of age and older are based on the severity of the patients' asthma.
- The maximum recommended dose is ADVAIR DISKUS 500/50 twice daily.
Improvement in asthma control following inhaled administration of ADVAIR DISKUS may occur within 30 minutes of starting treatment, although maximum benefit may not be achieved for a week or more after starting treatment. Individual patients will experience a variable time to onset and degree of symptom relief.
For patients who do not respond adequately to the initial dose after 2 weeks of treatment, replacement of the current strength of ADVAIR DISKUS with a higher strength may provide additional improvement in asthma control.
If a previously effective dosage regimen does not provide adequate improvement in asthma control, the therapeutic regimen should be reassessed and additional therapeutic options considered (eg, replacing the current strength of ADVAIR DISKUS with a higher potency, adding inhaled corticosteroids supplements, start oral corticosteroids).
Pediatric patients from 4 to 11 years
For patients with asthma aged 4 to 11 years who are not controlled with an inhaled corticosteroid, the dose is 1 inhalation of ADVAIR DISKUS 100/50 twice daily, approximately 12 hours apart.
Chronic obstructive pulmonary disease
The recommended dose for patients with COPD is 1 inhalation of ADVAIR DISKUS 250/50 twice daily, approximately 12 hours apart.
If shortness of breath occurs between doses, an inhaled short-acting beta2-agonist should be taken for immediate relief.
HOW SUPPLIED
Pharmaceutical forms and dosage
Powder for inhalation. Inhaler containing a strip of powder foil for oral inhalation. The strip contains a combination of fluticasone propionate 100, 250 or 500 mcg and salmeterol 50 mcg per blister.
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