Zofran (Ondansetron)

Zofran is used to prevent nausea and vomiting associated with chemotherapy or cancer surgery.

Dosage Quantity Price View
10 mg (EU2EU) 30
10 mg (EU2EU) 60
10 mg (EU2EU) 90
10 mg (EU2EU) 120
10 mg (EU2EU) 180

How is it used?

Zofran is used to prevent nausea and vomiting associated with cancer chemotherapy or surgery. Zofran is a serotonin 5-HT receptor blocker.3 It works by blocking a chemical that is thought to cause nausea and vomiting in certain situations (for example, chemotherapy).

For what conditions or diseases is this medicine prescribed?

Treats Nausea, Cancer Chemotherapy or Others

Zofran is used to prevent nausea and vomiting associated with cancer chemotherapy or surgery. Zofran is a serotonin 5-HT receptor blocker.3 It works by blocking a chemical that is thought to cause nausea and vomiting in certain situations (for example, chemotherapy).

DO NOT use Zofran if

  • are allergic to any ingredient in Zofran
  • is taking apomorphine.

Contact your doctor or healthcare provider immediately if any of these apply to you.

Some medical conditions may interact with Zofran. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you

  • if you are pregnant, planning to become pregnant, or are breastfeeding
  • if you are taking any prescription or non-prescription medicine, herbal preparation, or dietary supplement
  • if you are allergic to medicines, foods or other substances
  • if you have had an allergic reaction to another serotonin 5-HT3 receptor blocker (for example, dolasetron, granisetron)
  • if you have liver problems or a certain type of irregular heartbeat (QT prolongation, long QT syndrome).

Some medications may interact with Zofran. Tell your doctor if you are taking any other medicines, especially the following

  • Apomorphine because the risk of its side effects may be increased with Zofran
  • Antineoplastic agents (for example, cyclophosphamide) because their effectiveness may be reduced by Zofran.

This may not be a complete list of all interactions that may occur. Ask your doctor if Zofran may interact with other medications you take. Check with your doctor before starting, stopping, or changing the dose of any medicine.

Important safety information:

  • Zofran may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medications. Use Zofran with caution. Don't drive or do other potentially unsafe tasks until you know how you react to it.
  • Zofran should be used with extreme caution in children under 4 months of age; safety and efficacy in these children have not been confirmed. Certain concentrations of Zofran are not recommended in children. If you have any questions about the use of Zofran in children, ask your doctor or pharmacist.
  • Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Zofran during pregnancy. It is not known if Zofran is found in breast milk. If you are breast-feeding or are going to breast-feed while using Zofran, talk to your doctor. Discuss possible risks to your baby.

Use Zofran as directed on the package insert

How should this medicine be used?

Use Zofran as directed by your doctor.

  • Take Zofran with a full glass of water.
  • This medicine can be taken with or without food.
  • Do not take the medicine in larger amounts, or take it for longer than recommended by your doctor.
  • If you miss a dose of Zofran, take it as soon as possible. If it is almost time for the next dose, skip the missed dose and go back to your regular schedule. Do not take 2 doses at the same time.

Ask your doctor any questions you have about the use of Zofran.

What are the side effects that this medicine could cause?

Important safety information:

  • Zofran may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medications. Use Zofran with caution. Don't drive or do other potentially unsafe tasks until you know how you react to it.
  • Zofran should be used with extreme caution in children under 4 months of age; safety and efficacy in these children have not been confirmed. Certain concentrations of Zofran are not recommended in children. If you have any questions about the use of Zofran in children, ask your doctor or pharmacist.
  • Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Zofran during pregnancy. It is not known if Zofran is found in breast milk. If you are breast-feeding or are going to breast-feed while using Zofran, talk to your doctor. Discuss possible risks to your baby.

How is Zofran (Ondansetron) stored?

Store Zofran at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture and light. Do not store it in the bathroom. Keep Zofran out of the reach of children and away from pets.

what should I do in case of an overdose?

Important safety information:

  • Zofran may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medications. Use Zofran with caution. Don't drive or do other potentially unsafe tasks until you know how you react to it.
  • Zofran should be used with extreme caution in children under 4 months of age; safety and efficacy in these children have not been confirmed. Certain concentrations of Zofran are not recommended in children. If you have any questions about the use of Zofran in children, ask your doctor or pharmacist.
  • Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Zofran during pregnancy. It is not known if Zofran is found in breast milk. If you are breast-feeding or are going to breast-feed while using Zofran, talk to your doctor. Discuss possible risks to your baby.

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