DO NOT use Aldactone if:
- are allergic to any ingredient in Aldactone
- you are unable to urinate, have severe kidney problems, or have high levels of potassium in your blood
- you are taking a potassium supplement, another potassium-sparing diuretic (eg, amiloride, triamterene), or another aldosterone blocker (eg, eplerenone).
Contact your doctor or healthcare provider immediately if any of these apply to you.
Some medical conditions may interact with Aldactone. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breastfeeding
- if you are taking any medications, herbal preparations or dietary supplements, with or without a prescription
- if you are allergic to medicines, foods or other substances
- if you have high acidity in your body fluids; low blood sodium levels; high levels of potassium in the blood; kidney, liver, or heart disease; diabetes; or high levels of urea or nitrogen in the blood
- if you have a menstrual illness.
Some medications may interact with Aldactone. Tell your healthcare provider if you are taking any other medicines, especially any of the following:
- Adrenocorticotropic (corticotropin) hormone (ACTH) or corticosteroids (eg, prednisone) or because low blood electrolyte levels may occur
- Barbiturates (eg, phenobarbital) or narcotics (eg, morphine) because dizziness may occur when standing up
- Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), angiotensin II receptor antagonists (eg, valsartan), cyclosporine, macrolide immunosuppressants (eg, tacrolimus), other aldosterone blockers (eg, eplerenone), other potassium-sparing diuretics (eg, amiloride triamterene), or potassium supplements because elevated blood potassium levels may occur (eg, apathy, confusion, abnormal skin sensations in the arms and legs, heaviness in the extremities, slow heart rate, irregular heartbeat, life-threatening slow or irregular heartbeat)
- Non-steroidal anti-inflammatory drugs (NSAIDs) (eg, indomethacin) because they may decrease the effectiveness of Aldactone and increase the risk of kidney problems and high blood potassium
- Digoxin, digitoxin, lithium, nondepolarizing muscle relaxants (eg, tubocurarine), or quinidine because the risk of their side effects and toxicity may be increased with Aldactone
- Pressor amines (eg, norepinephrine) because their effectiveness may be decreased by Aldactone.
This may not be a complete list of all interactions that may occur. Ask your doctor if Aldactone might interact with other medications you take. Check with your doctor before starting, stopping, or changing the dose of any medicine.